Ultima-DES (1-3) 1mg IGF-1 LR3 Advanced Peptide Research Compound
Ultima-DES (1-3) 1mg IGF-1 LR3 also written as DES 1-3 IGF-1, Des(1-3)IGF-1, or DES IGF-1, is a truncated analogue of insulin-like growth factor-1 (IGF-1) that has attracted scientific intertest for research involving IGF signaling, receptor activity, cellular growth, and peptide biology.
Unlike full-length IGF-1, DES(1-3) IGF-1 lacks the first three amino acids at the N-terminal end of the molecule. This structural modification produces an important change in its interaction with insulin-like growth factor-binding proteins (IGFBPs). Research has demonstrated that DES(1-3) IGF-I has considerably reduced binding to IGFBPs compared with native IGF-I, allowing researchers to investigate IGF-related activity under different experimental conditions.
DES(1-3) IGF-1 for Research
DES(1-3) IGF-1 is primarily of interest in laboratory and biomedical research. Experimental studies have examined its effects on cellular hypertrophy, proliferation, differentiation, and growth-factor signaling. Published research has reported that DES(1-3) IGF-I can demonstrate substantially greater potency than IGF-I in certain experimental systems, an effect associated with its reduced interaction with IGF-binding proteins.
The peptide is therefore useful as a research tool for investigators studying the biological functions of the IGF system and the relationship between IGF-1, IGF receptors, and IGF-binding proteins.
Research Characteristics
- Product: DES(1-3) IGF-1
- Also known as: DES IGF-1, Des(1-3)IGF-1
- Molecular type: Truncated IGF-1 analogue
- Structure: 67 amino acids
- Research focus: IGF signaling and receptor-related activity
- Primary application: Laboratory and scientific research
DES(1-3) IGF-1 has also been investigated in cellular and animal research examining growth-factor responses and metabolic activity. These studies provide useful insight into the biological properties of modified IGF-1 molecules, but experimental findings should not be interpreted as evidence of established clinical benefits.
DES(1-3) IGF-1 Research Summary
For researchers investigating IGF-1 analogues, peptide signaling, IGF-binding proteins, and cellular growth pathways, DES(1-3) IGF-1 provides a distinctive molecular model. Its truncated structure and reduced IGFBP interaction make it valuable for studying how structural changes can influence IGF-related biological activity.





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